Sofdra (Sofpironium) for Hyperhidrosis

Overview
Sofdra is approved by the U.S. Food and Drug Administration (FDA) for the treatment of primary axillary hyperhidrosis in adults and children 9 and up. Sofdra is also known by its drug name, sofpironium.

Sofdra is an anticholinergic medication. It works by blocking the action of acetylcholine, a chemical in the body that stimulates sweat production, thereby reducing sweating in the treated area.

How do I take it?
Prescribing information states that Sofdra is applied as a topical gel. Generally, one pump is applied per underarm once a day at bedtime. It is important to use the medication exactly as prescribed by a health care provider.

Side effects
Common side effects of Sofdra include dry mouth, blurred vision, application site pain, application site erythema (discoloration), mydriasis (dilated pupils), application site dermatitis (skin inflammation), pruritus (itching) at the application site, urinary retention, and irritation at the application site.

Rare but serious side effects may include severe urinary retention, inability to sweat leading to overheating, and blurred vision that may affect the ability to operate machinery or drive. According to the prescribing information, people with certain medical conditions, such as glaucoma or Sjögren’s syndrome, should not use Sofdra due, as it can potentially worsen these conditions.

For more information about this treatment, visit:

Sofdra (Sofpironium) Topical Gel — U.S. Food and Drug Administration

Sofdra — Drugs.com